| Aerobic respiration | Anaerobic respiration |
| $(1)$ It uses oxygen for deriving energy. | $(1)$ It occurs in the absence of oxygen. |
| $(2)$ It occurs in cytoplasm and mitochondria. | $(2)$ It occurs in cytoplasm. |
| $(3)$ The end products are carbon dioxide and water. | $(3)$ The end products are ethyl alcohol and carbon dioxide (or lactic acid). |
| $(4)$ Complete oxidation of respiratory substrate takes place. | $(4)$ Incomplete oxidation of respiratory substrate takes place. |
| $(5)$ $36-38$ $ATP$ molecules are produced. | $(5)$ Only $2$ $ATP$ molecules are produced. |
| Glycolysis | Fermentation |
| $(1)$ Glycolysis occurs during both aerobic and anaerobic respiration. | $(1)$ Fermentation is a type of anaerobic respiration. |
| $(2)$ Pyruvic acid is produced as its end product. | $(2)$ Ethanol or lactic acid is produced as its end product. |
| Glycolysis | Citric acid Cycle (Krebs cycle) |
| $(1)$ It is a linear pathway. | $(1)$ It is a cyclic pathway. |
| $(2)$ It occurs in the cell cytoplasm. | $(2)$ It occurs in the mitochondrial matrix. |
| $(3)$ It occurs in both aerobic and anaerobic respiration. | $(3)$ It occurs only in aerobic respiration. |
| $(4)$ One glucose molecule generates $2$ $NADH$ and $2$ $ATP$ molecules. | $(4)$ It produces $6$ $NADH$, $2$ $FADH_2$, and $2$ $ATP$ molecules per glucose molecule. |
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